2s lipo and the bigger heavier tires will strip the diff very quickly even if the slipper is adjusted perfect. I found out the hard way, 4 times. I converted my 2s lipos to 1s2p and well.......
1s lipo + micro foams + theSteve's shock damping mod. + largest pinion + low ESR cap. on the battery input + lock the slipper = just about perfect for house running, nothing breaks, truck runs forever, wheelies on demand, just as fast as stock and motor stays cool.